Gabapentin is similar to Keppra® in terms of half-life and impact on dosing and steady-state. Accordingly, we suggest using Keppra recommendations for sample collection. The therapeutic range in humans of 12 to 21 mcg/ml may or may not be relevant in animals. We are concerned the oral bioavailability of gabapentin is variable in dogs and accordingly recommend monitoring in animals receiving gabapentin for seizure control.